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:: Volume 6, Issue 2 (11-2018) ::
JAIR 2018, 6(2): 61-72 Back to browse issues page
Investigating the effect of sub- letal concentration of cadmium On gene expression of cytochrome P450 CYP1A In the liver and gills tissues Cyprinus carpio
Abstract:   (3639 Views)
One of the most popular problem against fishes and human is marine pollution. Cadmium is one of the most important contaminating elements which has a significant role in making marine pollution. In this study we have concerned the effect of sub- letal toxicity in ion of cadmium on amount of gene expression cytochrome P450 (the gene is senative to contamination) in liver and gill of CyprinusCarpio has done under laborator conditions. After a scrod CyprinusCarpio put next to the cadmium with density (0.1 LC 50) sampling of their liver and gill are done on first, 7th and 14th day, in this tissues were collected the P450 gene expression level was determined by the method Realtime- PCR.  The results show Cadmium P450 CYP1A gene expression in liver tissue increased significantly(p<0.05) and P450 gene expression on the 1th and 14th day of exposure to Cadmium, increased significantly (p<0.05). Relative expression this gene of exposure to Cadmium in the liver was significantly upper than the gill (p<0.05) on the 14th day. Cadmium increased P450 CYP1A gene expression in this tissues.
 
Keywords: Biomarker, Cyprinus carpio, Marine contamination, Cadmium Chloride
Full-Text [PDF 396 kb]   (892 Downloads)    
Type of Study: Research | Subject: Special
Received: 2017/07/29 | Accepted: 2018/03/6 | Published: 2018/10/27
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Investigating the effect of sub- letal concentration of cadmium On gene expression of cytochrome P450 CYP1A In the liver and gills tissues Cyprinus carpio. JAIR 2018; 6 (2) :61-72
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Volume 6, Issue 2 (11-2018) Back to browse issues page
نشریه علمی پژوهشی پژوهشهای ماهی شناسی کاربردی Journal of Applied Ichthyological Research
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