In this trial, changes of metabolically indices such as cortisol, glucose, vitellogenin in blood, testosterone, progesterone, 17-β estradiol in females and 11-ketotestosteron and cortisol in males carp (Cyprinus carpio) in Bandar Turkmen (South of the Caspian Sea) were investigated. The results (independent t-test) indicated that the amount of cortisol and progesterone in wild females were significantly higher than wild cultivated females (P<0.05).  Also, the level of vitellogenin was significantly higher in wild females than wild cultivated females (P<0.05). However, the levels of 17-β estradiol, testosterone, glucose and calcium had no significant difference between wild and wild cultivated females (P>0.05). Also, the results of this study showed that the level of 11-ketotestosteron in wild male was significantly higher than wild cultivated male (P<0.05), and the level of cortisol in wild cultivated male was significantly higher than wild male (P<0.05).